摘要
Abstract
Objective To evaluate the cognitive function of patients with chronic cerebral circulation insufficiency who were older than 50 years ,and to investigate the significance of adding cognitive function scales in daily clinic service .Methods Patients with chronic cerebral circulation insufficiency were enrolled in the study between July 2011 and July 2013 .The investi-gation included two stages :screening and recheck . The screening stage was completed by mini-mental status estimate (MMSE) ,Hachinski ischemic score ,self-rating anxiety scale ,self-rating depression scale and transcranial Doppler examina-tion .Clinical dementia rating scale ,WMS-RC ,and cranial CT or MRI were performed in the recheck stage .Diagnostic criteria of mild cognitive impairment (MCI) referred to Perterson's diagnosis code and domestic standard .The threshold of MMSE for patients in this study was 24~26 .Results The score of MMSE was normal in 459 of 589 cases (77 .93% ) .MCI patients were 91 cases ;the detection rate was 15 .45% .55 cases of MCI were male and the positive rate was 9 .03% ,36 cases were female and the positive rate was 6 .12% .The detection rate increased with age advancing and decreased with education degree advan-cing .Taking the MMSE score as an independent variable and the age ,sexuality ,educational degree ,cerebrovascular risk fac-tor ,as dependent variable ,linear correlation analysis was accomplished .Significant correlation was found in educational de-gree ,age ,cerebrovascular risk factor (hypertension ,hypertension) and MMSE score .Conclusion In clinical practice ,patients with chronic cerebral circulation insufficiency and cerebrovascular risk factors are high risk group of MCI .Increase the cognitive function scale test is helpful for early prevention and treatment of MCI in clinical routine .关键词
轻度认知功能障碍/认知功能评定/脑血管危险因素Key words
Mild cognitive impairment/Mini-mental status estimate/Cerebral vascular/Risk factors分类
医药卫生
