华西口腔医学杂志Issue(1)：66-70,5.DOI:10.7518/hxkq.2014.01.016
牙周基础治疗对伴2型糖尿病的中、重度牙周炎患者牙周炎症控制、血清炎症指标及代谢水平影响
Effects of non-surgical periodontal treatment on clinical response, serum inflammatory parameters, and metabolic control of type 2 diabetes patients with moderate to severe periodontitis
摘要
Abstract
Objective To evaluate the effects of periodontal treatment on the clinical response, systemic inflammatory parameters, and metabolic control of type 2 diabetes patients with moderate to severe periodontitis. Methods A total of 56 patients with mean clinical attachment level (CAL)>3 mm were included in the subgroup analysis. A repeated-measures ANOVA (group factor: treatment group and control group; time factor: initial visit, 1.5, 3, and 6 months) was used to analyze the probing depth (PD), CAL, bleeding on probing (BOP), high-sensitivity C-reactive protein (hsCRP), glycated hemoglobin (HbA1c), and fasting plasma glucose. Results Significantly lower PD (F=62.898,P=0.000), CAL (F=51.263,P=0.000), BOP (F=75.164,P=0.000), hsCRP (F=6.391, P=0.010), HbA1c (F=4.536, P=0.011), and fasting plasma glucose level (F=3.073,P=0.031) were observed after therapeutic periodontal improvement. The inter-group differences for PD (t=-2.050, P=0.045), BOP (t=-4.538,P=0.000), and hsCRP (t=-2.261, P=0.028) were statistically significant after therapy. Conclusion Non-surgical periodontal treatment can effectively improve periodontal status, circulating inflammatory status, and metabolic control of diabetic patients with moderate to severe periodontitis.关键词
牙周炎/糖尿病/超敏C反应蛋白Key words
periodontitis/diabetes/high-sensitivity C-reactive protein分类
医药卫生引用本文复制引用
陈蕾,苏媛,倪佳,罗维,轩东英,章锦才..牙周基础治疗对伴2型糖尿病的中、重度牙周炎患者牙周炎症控制、血清炎症指标及代谢水平影响[J].华西口腔医学杂志,2014,(1):66-70,5.基金项目
科技部“十一五”重点支撑计划基金资助项目（2007BAI-18B02）；广东省科技计划基金资助项目 （）
