摘要
Abstract
Objective:To investigate the pathology diagnosis and differential diagnosis of the oarian maturity cystic teratoma with squamous cell carcinoma. Methods:To analyse the clinical da-ta,iconography and pathology features of one oarian maturity cystic teratoma with squamous cell car-cinoma,and to carry on literature review. Results:Gross appearance:gray beige cystic neoplasm, 18 cm × 11 cm × 7 cm,cyst wall smooth containing lipid and hair,can be stripped,without the liq-uid and mucus composition. There is 4 cm × 3 cm gray solid area with the gray fragile texture of cross section. Microscopically appearance:tumor wall lines squamous epithelium,with the sebaceous glands and hair follicles inside the wall;Visible scattered cells with big hyperchromatic nuclears, showed diffuse arrangement,faint nucleoli,some cells with a spindle type,another little differenti-ated squamous cell carcinoma area can be visible,which shows the cornification in cell and cell bridges and horny pearl. Immunohistochemical stains results,CK5/6 and PCK:the malignant cells express positively;The pathological diagnosis:ovarian maturity cystic teratoma with area of squa-mous cell carcinoma in middle-low differentiation. Conclusion:Ovarian maturity cystic teratoma with squamous cell carcinoma is a rare highly malignant tumor,the patients age and postmenopausal age,tumor size,standard pathology examination and distinctive immunohistochemical mark are helpfull to the pathological diagnosis and differential diagnosis.关键词
卵巢肿瘤/成熟性囊性畸胎瘤伴继发性改变/病理学诊断/鉴别诊断Key words
ovary neoplasms/maturity cystic teratoma with secondary changes/pathology diagnosis/differential diagnosis分类
医药卫生
