检验医学与临床Issue(17)：2211-2212,2.DOI:10.3969/j.issn.1672-9455.2013.17.002
373株肺炎克雷伯菌的分布及耐药性分析
Distribution and drug resistance analysis of 373 strains of Klebsiella pneumoniae
摘要
Abstract
Objective To explore the distribution characteristics and drug resistance of Klebsiella pneumoniae in Hainan area .Methods Clinical distribution characteristics and results of drug sensitivity test of 373 strains of Klebsiella pneumoniae from August 2010 to August 2011 were retrospectively analyzed .All strains were identified and detected for drug sensitivity by using VITEK 2 Compact automatic microorganism identification and susceptibili-ty system .Results Most of the 73 strains of Klebsiella pneumoniae were isolated from specimens of sputum ,feces , urine ,secretion ,blood and liquor puris .Drug resistance rate of Klebsiella pneumoniae to imipenem was the lowest , followed by ertapenem ,cefotetan ,piperacillin/tazobactam ,and amikacin .Drug resistance rate to ampicillin was the highest ,followed by nitrofurantoin ,cefazolin and ampicillin/sulbactam .The detection rate of strains producing ex-tended-spectrum β-lactamases (ESBLs) was 32 .00% .Conclusion Clinical infection of Klebsiella pneumoniae might be common ,most of which could be infection of respiratory tract ,urinary tract and others ,and the clinical strains might be multiple drug resistance ,which should be paid more attention .Antimicrobial drugs should be rationally used to reduce the drug resistance rate .Strains ,producing ESBLs or with multiple drug resistance ,should be moni-tored for resistance gene and drug resistance ..关键词
肺炎克雷伯菌/病原菌/耐药性Key words
Klebsiella pneumonia/pathogen/drug resistance引用本文复制引用
韦衍莉,陈如寿,范志刚..373株肺炎克雷伯菌的分布及耐药性分析[J].检验医学与临床,2013,(17):2211-2212,2.基金项目
2012年海南省自然科学基金项目（项目编号812199）。 （）
