检验医学与临床Issue(17)：2252-2253,2255,3.DOI:10.3969/j.issn.1672-9455.2013.17.021
术前辅助放化疗对低位直肠癌患者保肛率及术后并发症的影响
Influence of preoperative chemoradiotherapy on sphincter preservation and postoperative complications in patients with low rectal carcinomas
摘要
Abstract
Objective To study the influence of preoperative chemoradiotherapy on sphincter preservation and postoperative complications in patients with low rectal carcinomas .Methods Clinical data of 90 patients with low rectal carcinomas in this hospital from 2007-2012 were retrospectively analyzed .45 patients receiving preoperative chemoradiotherapy were divided into experiment group ,while 45 patients who didn′t receive preoperative chemora-diotherapy were divided into control group .Intraoperative situation ,sphincter preservation ,postoperative complica-tions and cellular immune function before and after operation of the two groups were compared .Results There were no significant differences of mean amount of bleed [(95 .2 ± 12 .8) mL vs .(98 .4 ± 14 .6) mL ,P>0 .05] ,mean opera-tive time [(117 .3 ± 14 .8) min vs .(121 .5 ± 15 .2)min ,P>0 .05] ,incidences of postoperative complications (6 cases vs .3 cases ,P>0 .05) and cellular immune function before and after the operation between the two groups .The sphincter preservation rate of experiment group was statistically higher than that of control group (51 .1% vs . 11 .1% ,P<0 .05) .Conclusion Preoperative chemoradiotherapy could improve the sphincter preservation rate in pa-tients with low rectal carcinomas ,which would not increase the incidences of postoperative complications and damage the cellular immune function of patients .关键词
术前放化疗/低位直肠癌/保肛率/术后并发症Key words
preoperative chemoradiotherapy/low rectal carcinoma/sphincter preservation rate/postop-erative complications引用本文复制引用
秦尚学,张晓龙,陈晓斌..术前辅助放化疗对低位直肠癌患者保肛率及术后并发症的影响[J].检验医学与临床,2013,(17):2252-2253,2255,3.
