摘要
Abstract
Objective To study the clinical effect of amiodarone in the treatment of arrhythmia in emergent coronary heart disease (CHD) .Methods From Nov .2010 to Nov .2012 ,90 patient with emergent CHD arrhythmia were divided into control group (45 cases) ,receiving routine treatment combined with propafenone ,and observation group (45 cases) , receiving routine treatment combined with amiodarone . Indicators ,including atrial fibrilation (AF) converting rate within 24 hours ,clinical curative effect ,in - hospital mortality and infarction rate were com-pared between the two groups .Results In observation group ,the number of patients with markedly effectiveness , effectiveness and non - effectiveness were 37 ,5 and 3 cases ,and those of control group were 28 ,8 and 9 cases .The effectiveness rate of observation group was 93 .3% ,higher than the 80 .0% of control group (P< 0 .05) .The recur-rence rate of chest pain was 2 .22% (1/45) in observation group ,lower than the 8 .90% (4/45) in control group (P<0 .05) .The ventricular rate 24 hours after treatment in observation group was (73 ± 6)times/min ,significantly lower than the (89 ± 9)times/min of control group (P < 0 .05) .The AF converting rate with 24 hours ,clinical effective-ness ,in - hospital mortality and infarction rate in observation group were superior to control group (P< 0 .05) .The HR in observation group were significantly decreased after treatment and restored to the normal range (P< 0 .01) , QTc were significantly increased (P< 0 .01) and QTd were significantly reduced (P< 0 .01) .Conclusion Amioda-rone could quickly promote the restoring of sinus rhythm in patients with emergent CHD arrhythmia ,and could be relatively safe ,reliable and worthy for clinical promotion .关键词
胺碘酮/冠心病/快速心律失常/临床效果Key words
amiodarone/coronary heart disease/rapid arrhythmia/clinical effect
