检验医学与临床Issue(20)：2673-2674,2.DOI:10.3969/j.issn.1672-9455.2013.20.016
2项肿瘤标志物检测对Ⅳ期胃癌腹膜转移的鉴别诊断价值
Clinical value of CEA combined with CA19-9 in the diagnosis of stage Ⅳ gastric cancer peritoneal metastasis
王成芳1
作者信息
- 1. 江苏省扬中市人民医院检验科，江苏镇江 212200
- 折叠
摘要
Abstract
Objective To explore the clinical value of serum carcinoembryonic antigen (CEA) combined with carbohydrate antigen 19-9(CA19-9) in the diagnosis and differential diagnosis of stage Ⅳ gastric cancer peritoneal metastasis .Methods Enzyme coupling adsorption method and chemiluminescence immune assay were used to detec-ted serum CEA and CA19-9 levels in gastric cancer patients with or without peritoneal metastasis (metastasis group and non-metastasis group) and healthy subjects (control group) ,and the results were statistically analyzed .Results Serum levels of CEA and CA19-9 were(58 .42 ± 9 .61)μg/L and(72 .55 ± 13 .73)U/mL in metastasis group ,which were significantly higher than the other two groups(P<0 .05) ,and those in non -metastasis group were(27 .41 ± 13 .84)μg/L and(33 .49 ± 9 .37)U/mL ,which were higher than control group(P<0 .05) .The positive rates of serum CEA and CA19-9 were higher than non -metastasis group .In metastasis patients ,serum CEA and CA19-9 levels were correlated with tumor size ,lymph node metastasis and ascites .Conclusion CEA and CA19-9 level could play an important role in the diagnosis of stage Ⅳ gastric cancer peritoneal metastasis ,and combined detection of the two in-dicators could be used for diagnosis .关键词
癌胚抗原/糖链抗原19-9/Ⅳ期胃癌/腹膜转移Key words
carcinoembryonic antigen/carbohydrate antigen 19-9/stage Ⅳ gastric cancer/peritoneal metastasis引用本文复制引用
王成芳..2项肿瘤标志物检测对Ⅳ期胃癌腹膜转移的鉴别诊断价值[J].检验医学与临床,2013,(20):2673-2674,2.
