检验医学与临床Issue(21)：2820-2821,2.DOI:10.3969/j.issn.1672-9455.2013.21.018
胱氨酸蛋白酶抑制剂C对早期糖尿病肾病的诊断价值
Diagnostic value of cystine protease inhibitor C in early diabetic nephropathy
何健 1严海燕 1庄豪 1罗晓红1
作者信息
- 1. 中山大学孙逸仙纪念医院检验科，广州 510120
- 折叠
摘要
Abstract
Objective To investigate the diagnostic value of serous cystine protease inhibitor C (CysC) in early diabetic nephropathy .Methods Total of 251 cases of early diabetic kidney disease were screened from medical data base of the Second Affiliated Hospital of SUMS (from Jan .2006 to Dec .2012) ,according to value of urinous albumin , were divided into group of normal-albumin(UAER<20 μg/min ,n=96) ,micro-albumin(20 μg/min≤ UAER<200μg/min ,n=82) ,clinical-albumin group(UAER≥200 μg/min ,n=73) ,and there were 100 healthy volunteers as con-trol group .Serous concentrations of CysC ,BUN ,and Crea in 4 groups were detected and the parameters were ana-lyzed by ANOVA .Results Value of CysC in normal-albumin group was similar to that in control group (P>0 .05) . However ,the value of CysC in micro-albumin group and clinical-albumin group was significantly higher than that in normal-albumin and control group(P<0 .01) .No significant difference had been found in value of serous BUN and Crea among control ,normal-albumin and micro-albumin groups(P>0 .05) ,and the value of serous BUN and Crea in clinical-albumin group was the highest compared with that in other groups (P<0 .01) .Conclusion Comparing with BUN and Crea ,concentration of serous CysC was beneficial for the diagnosis of early diabetic nephropathy .关键词
糖尿病肾病/血清胱氨酸蛋白酶抑制剂C/尿清蛋白Key words
diabetic nephropathy/serum cystine protease inhibitor C/urinous albumin引用本文复制引用
何健,严海燕,庄豪,罗晓红..胱氨酸蛋白酶抑制剂C对早期糖尿病肾病的诊断价值[J].检验医学与临床,2013,(21):2820-2821,2.
