检验医学与临床Issue(21)：2822-2823,2.DOI:10.3969/j.issn.1672-9455.2013.21.019
创伤脓毒症患者外周血Th17／Treg水平变化及临床意义
Th17/Treg balance in peripheral blood in patients with posttraumatic sepsis and its clinical significance
徐斌 1车立新2
作者信息
- 1. 新疆维吾尔自治区富蕴县人民医院外科 836100
- 2. 新疆维吾尔自治区人民医院骨二科830000
- 折叠
摘要
Abstract
Objective To investigate the changes of Th17/Treg levels of peripheral blood in patients with posttraumatic sepsis and the clinical significance .Methods 40 cases of traumatic sepsis were enrolled as study group from 2010 January to 2011 December in our hospital ,40 cases of trauma without sepsis as control group 1 and 40 healthy subjects as control group 2 .The Th17 and Treg level in blood were detected by flow cytometry in three groups .Results The peripheral blood Th17/Treg value in study group value was higher than that of control group 1 and control group 2 ,and the difference was significant(P<0 .05) .While there was no difference in Th17/Treg 1 val-ue of peripheral blood between the control group 1and control group 2(P> 0 .05) .In the study group ,peripheral blood Th17/Treg value in patients with different severity was not the same ,and peripheral blood Th17/Treg value in septic shock patients was higher than that in patients with severe sepsis patients ,the latter was higher than that in mild sepsis patients ,and the difference was significant(P<0 .05) .Conclusion The level of Th17/Treg of peripheral blood in sepsis patients was abnormally increased ,along with the aggravation of the severity of sepsis .The detection of peripheral blood Th17/Treg level could judge the pathogenetic condition of sepsis ,and it has importantly practical significance in clinical practice .关键词
创伤脓毒症/外周血/Th17/TregKey words
wound sepsis/peripheral blood/Th17/Treg引用本文复制引用
徐斌,车立新..创伤脓毒症患者外周血Th17／Treg水平变化及临床意义[J].检验医学与临床,2013,(21):2822-2823,2.
