摘要
Abstract
Objective To investigate the clinical effect of telmisartan on treatment of diabetes with hyperten-sion .Methods Ninety cases of diabetic with hypertension from September 2009 to January 2012 in our hospital were randomly divided into treatment group and control group ,45 cases in each group .The patients in control group were treated with amlodipine ,and patients in the treatment group were treated with telmisartan based on the amlodipine treatment .The changes of fasting blood glucose ,total cholesterol and triglyceride were detected before and after treatment ,and the total efficiency and adverse reactions were compared between the two groups .Results After treat-ment ,fasting blood glucose ,total cholesterol and triglycerides of the treatment group decreased than before treat-ment ,and the difference was statistically significant (P< 0 .05) .The total effective rate of the control group was 62 .2% ,the total effective rate of the treatment group was 88 .9% ,and the difference was significant(P<0 .05) .The therapeutic effect of treatment group was significantly better than that of the control group .The adverse reaction rate of the control group was 15 .6% ,that of the treatment group was 17 .8% ,but the difference was not statistically sig-nificant(P>0 .05) .Conclusion Treatment of telmisartan in patients with diabetes and hypertension can significantly improve the patients′fasting blood glucose ,total cholesterol ,triglycerides levels and clinical symptoms ,the treatment effectiveness is significant ,with no increase on adverse reactions ,and it is worthy of clinical application .关键词
糖尿病/高血压/替米沙坦Key words
diabetes/hypertension/telmisartan
