检验医学与临床Issue(23)：3146-3147,2.DOI:10.3969/j.issn.1672-9455.2013.23.029
结核性胸膜炎患者3个项目检测及其临床意义
Clinical value about the united test of serum IL-2R 、TNF-α and PCT concentration in patients with tuberculous pleurisy
叶志坚 1王霞芳 1肖玉梅 1施美华 1朱雪峰 1陈兴年 1张耀刚1
作者信息
- 1. 江苏省苏州市第五人民医院结核病科 215007
- 折叠
摘要
Abstract
Objective To investigate the changes of concentration of interlukin-2 receptor(IL-2R) ,tumor nec-rosis factor-α(TNF-α) and procalcitonin(PCT ) in patients with tuberculous pleurisy ,to explore the relationship be-tween these detections with clinical symtoms .Methods Fifty patients diagnosed as tuberculous pleurisy were chosen as test group ,and the serum concentrations of IL-2R ,TNF-α and PCT in these patients were measured by the method of enzyme - linked immunosobent assay(ELISA) ,both before and after the treatment .Forty healthy people were cho-sen as control group ,and their serum concentrations of IL-2R ,TNF-α and PCT were also detected by ELISA .Results The serum concentrations of IL-2R ,TNF-α and PCT in patients with tuberculous pleurisy before treatment were sig-nificantly higher than those in normal control group(P< 0 .01) ;after the treatment ,there was no difference in the se-rum concentrations of IL-2R ,TNF-α and PCT between these patients in experimental group and those in healthy con-trol group(P> 0 .05) .Conclusion IL-2R ,TNF-αand PCT play an important role in the pathogenesis of tuberculous pleurisy ,and they could be one of the most important diagnostic evidences ,and they also have clinical values for the treatment and prognosis of this disease .关键词
结核性胸膜炎/白细胞介素-2 受体/肿瘤坏死因子-α/降钙素原Key words
tuberculous pleurisy/interlukin-2 receptor/tumor necrosis factor-α/procalcitonin引用本文复制引用
叶志坚,王霞芳,肖玉梅,施美华,朱雪峰,陈兴年,张耀刚..结核性胸膜炎患者3个项目检测及其临床意义[J].检验医学与临床,2013,(23):3146-3147,2.
