检验医学与临床Issue(24)：3260-3262,3.DOI:10.3969/j.issn.1672-9455.2013.24.006
糖原磷酸化酶同工酶 BB 对急性冠状动脉综合征早期诊断价值
The value of glycogen phosphorylase isoenzyme BB in the early diagnosis of acute coronary syndrome
摘要
Abstract
Objective To detect the level of glycogen phosphorylase isoenzyme BB (GPBB) and explore the early diagnosis value of it in acute coronary syndrome(ACS) .Methods Eighty-four patients with ACS(ACS group) and 20 healthy people with physical examination in the same period (control group) were collected ,ACS group was di-vided into 5 subgroups(0-2 ,3 -4 ,5 -6 ,7 -12 ,13 -24 h) according to the time of the chest pain onset ,serum GPBB ,troponin T(cTnT) and myoglobin(Mb)were detected in all selected candidates .Results Compared with the control group ,GPBB ,cTnT and Mb levels in ACS group were higher [(5 .74 ± 2 .67 vs 3 .25 ± 0 .77)ng/mL ,(1 .10 ± 2 .18 vs 0 .01 ± 0 .01)ng/mL ,(276 .30 ± 378 .26 vs 35 .85 ± 10 .73)ng/mL ,P< 0 .05] .The overall positive rate of GPBB in 0-2 h group(76 .47% ) was higher than cTnT (35 .29% )and Mb(41 .18% )(P<0 .05) .The AUC of GPBB in 0-4 h group was significantly greater than cTnT and Mb (0 .922 ,0 .732 ,0 .823 ,P< 0 .05) .Conclusion GPBB could be used for the early diagnosis of ACS .关键词
急性冠状动脉综合征/糖原磷酸化酶同工酶BB/早期诊断Key words
acute coronary syndrome/glycogen phosphorylase isoenzyme BB/eargly diagnosis引用本文复制引用
杨云净,罗艳..糖原磷酸化酶同工酶 BB 对急性冠状动脉综合征早期诊断价值[J].检验医学与临床,2013,(24):3260-3262,3.基金项目
国家临床重点专科建设项目经费资助（财社［2010］305号）。 （）
