检验医学与临床Issue(5)：589-591,594,4.DOI:10.3969/j.issn.1672-9455.2014.05.005
某院2008～2012年儿科血培养病原菌变迁及耐药谱分析
The analysis of distribution and sensitivity of etiology of blood infection in pediatric patients from 2008 to 2012
陈怡丽 1郭鹏豪 1黄汉 1廖康 1刘丹2
作者信息
- 1. 中山大学附属第一医院医学检验部，广州 510080
- 2. 中山大学医学检验系，广州 510080
- 折叠
摘要
Abstract
Objective To investigate the distribution of pathogenic bacteria isolated from blood culture of pedi-atric patients and observe the antibiotic sensitivity of these bacteria so as to provide the reference for clinical antimi-crobial usage .Methods The results of drug susceptibility and distribution of pathogens isolated from blood culture of children from January 2008 to December 2012 were analyzed .The antimicrobial susceptibility rates and pathogens dis-tribution were analyzed by WHONET 5 .6 software .Results Three hundred and twelve strains of pathogens were i-solated ,and the main pathogenic bacteria included 122 strains of Gram positive bacteria and 190 strains of Gram nega-tive bacteria ,most of which was Klebsiella pneumoniae with the percentage of 25 .96% .Noteworthily ,51 .60% of the positive blood curltures were from paediatric patients with hematopathy .Most of Gram positive bacteria were sensi-tive to Vancomycin ,Tiecoplanin and Linezolid ,while most of Gram negative bacillus were sensitive to Carbopenem antibiotics and resistant to most of other antibiotics such as Ampicillin and the cephalosporin antibiotics .Conclusion Most of bacteria isolated from children with bloodstream infection were Gram negative bacteria .Pathogens were high-ly resistant to common antibiotics such as Penicillin antibiotics and cephalosporin .It night be important to use antibi-otics rationally and according to drug sensitivity test to use antibiotics so as to reduce the occurrence of bacterial re-sistance .关键词
儿童/血培养/病原菌/药敏分析Key words
pediatric/blood culture/pathogen/drug susceptibility引用本文复制引用
陈怡丽,郭鹏豪,黄汉,廖康,刘丹..某院2008～2012年儿科血培养病原菌变迁及耐药谱分析[J].检验医学与临床,2014,(5):589-591,594,4.
