检验医学与临床Issue(5)：592-594,3.DOI:10.3969/j.issn.1672-9455.2014.05.006
脑脊液乳酸在术后感染中的临床价值
Clinical application of cerebrospinal fluid lactate in neurosurgical postoperative infection
摘要
Abstract
Objective To evaluate the value of the cerebrospinal fluid lactic acid levels in the diagnosis and prognosis of postoperative intracranial infection .Methods One hundred and twenty six nervous system disease pa-tients accepted surgery were selected in August 2008 to January 2013 ,and divided into two groups ,46 cases in the in-fection group ,80 cases in the non infected group .In addition ,50 cases with no nervous system disease and no opera-tion were selected into the control group .After cases in the infection group accepted surgery seven days ,the concen-tration of lactic acid in the cerebrospinal fluid(csf-LA) ,cerebrospinal of glucose (csf-GLU) ,cerebrospinal fluid pro-tein(csf-Pro) ,cerebrospinal fluid white blood cell count (csf-WBC) were determined respectively in the three groups . Moreover ,cases in the infection group were divided into good surgical result group ,bad surgical result group and death group ,csf-LA was tested after surgery 7 ,9 ,11 ,15 days in the three groups respectively .Results The concen-tration of csf-LA in cases of infection group was obviously higher than that of control group and non infected group ;Non infected group was significantly higher than the control group ,the difference had statistical significance (P<0 .01) .csf-LA was significantly associated with csf-Pro and csf-WBC of the infection group respectively at the differ-ent phase (r=0 .721 ,P<0 .01 ;r=0 .654 ,P<0 .05) ,and unrelated with csf-GLU (r=0 .125 ,P>0 .05) .csf-LA in cases of good surgical group was significantly lower than the bad surgical group and the death group at the different phase(P<0 .05) ,csf-LA in bad surgical result group was significantly lower than that in the death group (P<0 .01) . Conclusion Cerebrospinal fluid lactate levels has important value in the diagnosis ,efficacy and prognosis of patients with intracranial infectione after surgery .关键词
颅内感染/脑脊液/颅脑术后/乳酸Key words
intracranial infection/cerebrospinal fluid/craniocerebral surgery/lactic acid引用本文复制引用
刘小玲,廖群,易良,邓婷..脑脊液乳酸在术后感染中的临床价值[J].检验医学与临床,2014,(5):592-594,3.基金项目
重庆市自然科学基金资助项目（cstc2012ijA0306）。 （）
