检验医学与临床Issue(5)：621-622,625,3.DOI:10.3969/j.issn.1672-9455.2014.05.018
维持性血液透析患者血浆 D-二聚体及纤溶系统变化研究
Changes of the fibrinolytic system and the level of plasma D-dimer in maintenance hemodialysis patients
蒋玲 1安仲武 1秦继宝 1陈丽梅1
作者信息
- 1. 江苏省连云港市东方医院检验科 222042
- 折叠
摘要
Abstract
Objective To observe the effect of maintenance hemodialysis(MHD) on the changes of plasma D dimer and fibrinolytic system ,to study the effect of M HD on the fibrinolytic system and the level of plasma D dimer . Methods The D dimer ,FDP ,t-PA and PAI levels were determined in 50 M HD patients before and after dialysis ,60 healthy subjects were selected into control group .Results The plasma D-dimers ,FDP and t-PA in group M HD were significantly higher than the control group before dialysis (P< 0 .01);PAI was significantly lower than the control group .After dialysis the levels of plasma D dimers ,FDP and t-PA increased significantly ;while PAI was significantly lower than before dialysis(P<0 .01) .Conclusion The patients with MHD have coagulation and fibrinolysis system disorder ,hemodialysis makes it more obvious .关键词
维持性血液透析/D-二聚体/纤维蛋白降解产物/组织纤溶酶原激活物/纤溶酶原激活物抑制物Key words
maintenance Hemodialysi/D-dimer/fibrin degradation product/tissue type plasminogen ac-tivator/plasminogen activator inhibitor引用本文复制引用
蒋玲,安仲武,秦继宝,陈丽梅..维持性血液透析患者血浆 D-二聚体及纤溶系统变化研究[J].检验医学与临床,2014,(5):621-622,625,3.
