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丙型肝炎病毒抗体联合核酸定量检测对丙型肝炎患者的早期诊断价值研究

杨平 毕永春 胡伟 张葵

检验医学与临床Issue(8):1020-1022,3.
检验医学与临床Issue(8):1020-1022,3.DOI:10.3969/j.issn.1672-9455.2014.08.006

丙型肝炎病毒抗体联合核酸定量检测对丙型肝炎患者的早期诊断价值研究

Clinical value of HCV Ab and HCV RNA titers for the early diagnosis of hepatitis C

杨平 1毕永春 1胡伟 1张葵1

作者信息

  • 1. 南京大学医学院附属鼓楼医院检验科,南京 210008
  • 折叠

摘要

Abstract

Objective To explore the value of hepatitis C virus antibody (HCV Ab) and hepatitis C virus nu-cleic acid (HCV RNA ) for the diagnosis of hepatitis C .Methods Real-time fluorescence quantitative polymerase chain reaction (FQ-PCR) was used to detect HCV RNA ,enzyme-linked immunosorbent assay (ELISA) and colloidal gold labeled method was used to detect HCV Ab ,and the rate method was used to detect alanine aminotransferase (ALT ) in 116 patients with hepatitis C .Results The positive ratios of HCV Ab detected by ELISA ,HCV RNA , HCV Ab detected by colloidal gold labeled method and ALT were respectively 83 .6% ,73 .3% ,66 .4% and 59 .5% . Positive rated of joint determination of HCV Ab and HCV RNA was 100 .0% .Conclusion Combined detection of HCV Ab and HCV RNA could be conducive to the diagnosis of hepatitis C .

关键词

丙型肝炎诊断/丙型肝炎病毒抗体/丙型肝炎病毒核酸

Key words

diagnosis of hepatitis C/HCV antibody/HCV RNA

引用本文复制引用

杨平,毕永春,胡伟,张葵..丙型肝炎病毒抗体联合核酸定量检测对丙型肝炎患者的早期诊断价值研究[J].检验医学与临床,2014,(8):1020-1022,3.

基金项目

江苏省南京市医学科技发展基金资助项目(YKK09113)。 ()

检验医学与临床

OACSTPCD

1672-9455

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