检验医学与临床Issue(8):1020-1022,3.DOI:10.3969/j.issn.1672-9455.2014.08.006
丙型肝炎病毒抗体联合核酸定量检测对丙型肝炎患者的早期诊断价值研究
Clinical value of HCV Ab and HCV RNA titers for the early diagnosis of hepatitis C
摘要
Abstract
Objective To explore the value of hepatitis C virus antibody (HCV Ab) and hepatitis C virus nu-cleic acid (HCV RNA ) for the diagnosis of hepatitis C .Methods Real-time fluorescence quantitative polymerase chain reaction (FQ-PCR) was used to detect HCV RNA ,enzyme-linked immunosorbent assay (ELISA) and colloidal gold labeled method was used to detect HCV Ab ,and the rate method was used to detect alanine aminotransferase (ALT ) in 116 patients with hepatitis C .Results The positive ratios of HCV Ab detected by ELISA ,HCV RNA , HCV Ab detected by colloidal gold labeled method and ALT were respectively 83 .6% ,73 .3% ,66 .4% and 59 .5% . Positive rated of joint determination of HCV Ab and HCV RNA was 100 .0% .Conclusion Combined detection of HCV Ab and HCV RNA could be conducive to the diagnosis of hepatitis C .关键词
丙型肝炎诊断/丙型肝炎病毒抗体/丙型肝炎病毒核酸Key words
diagnosis of hepatitis C/HCV antibody/HCV RNA引用本文复制引用
杨平,毕永春,胡伟,张葵..丙型肝炎病毒抗体联合核酸定量检测对丙型肝炎患者的早期诊断价值研究[J].检验医学与临床,2014,(8):1020-1022,3.基金项目
江苏省南京市医学科技发展基金资助项目(YKK09113)。 ()