检验医学与临床Issue(8)：1023-1024,1027,3.DOI:10.3969/j.issn.1672-9455.2014.08.007
二仙汤加芪海消瘿汤治疗慢性淋巴细胞性甲状腺炎伴甲状腺功能减退症的临床研究
Application of ER Xian Tang and QI Hai Xiao Ying Tang for the treatment of chronic lymphocytic thyroiditis complicat-ed with hypothyroidism
摘要
Abstract
Objective To explore the curative effects of ER Xian Tang and QI Hai Xiao Ying Tang for the treatment of chronic lymphocytic thyroiditis (CLT ) complicated with hypothyroidism .Methods A total of 70 pa-tients with CLT complicate with hypothyroidism were divided into treatment group ,given Er Xian Tang ,Qi Hai Xiao Ying Tang and levothyroxine sodium tablets ,and control group ,given evothyroxine sodium tablets .Curative effects , and serum levels of triiodothyronine (T3) ,thyroxine (T4) ,free triiodothyronine (FT3) ,free thyroxine (FT4) ,thyro-tropic-stimulating hormone (TSH) ,thyroglobulin antibody (TGAb) ,thyroid peroxidase antibody (TPOAb) and so on were compared between the two groups .Results Before treatment ,the differences of levels of T3 ,T4 ,TSH ,FT3 , FT4 ,TGAb ,TPOAb and indexes of routine blood test between the two groups were not significant (P>0 .05) ,and liver function of patients in the two groups were all without abnormality .After treatment ,the effective rate in treat-ment group was 91 .4% ,being significantly different with the 74 .3% in control group (P<0 .05) .After treatment , levels of T3 ,T4 ,FT3 ,FT4 and TSH in the two groups all return to normal range ,and levels of TGAb and TPOAb in treatment group were reduced ,being significantly different with levels detected before treatment and with levels of control group (P<0 .05) .In treatment group ,the dosage of levothyroxine reduced significantly (P<0 .05) .Thyroid volume reduced significantly only in treatment group (P<0 .05) .Conclusion Er Xian Tang and Qi Hai Xiao Ying Tang could effectively regulate immune function ,reduce levels of TGAb ,TPOAb and thyroid volume in patients with CLT complicated with hypothyroidism .关键词
中药/慢性淋巴细胞性甲状腺炎/甲状腺功能减退/左旋甲状腺素钠Key words
traditional Chinese medicine/chronic lymphocytic thyroiditis/hypothyroidism/levothyroxine引用本文复制引用
陈琼科,郑世霞,刘静..二仙汤加芪海消瘿汤治疗慢性淋巴细胞性甲状腺炎伴甲状腺功能减退症的临床研究[J].检验医学与临床,2014,(8):1023-1024,1027,3.基金项目
重庆市卫生局资助项目（2006-20）。 （）
