昆明医科大学学报Issue(9)：29-30,37,3.
天麻素对老年痴呆树鼩海马BDNF表达的影响
Effects of Gastrodin on BDNF Expression in AD Tree Shrew
摘要
Abstract
Objective To investigate the effect of gastrodin on brain-derived neurotrophic factor (BDNF) expression in Alzheimer's disease ( AD) tree shrew. Methods AD tree shrew model was established by intracerebroventricular injection with amyloid-βpeptide (Aβ) . Since the eighth day after injection, the tree shrews were treated with gastrodin for thirty days. The expression of BDNF in tree threw hippocampus was detected by reverse transcription polymerase chain reaction (RT-PCR) . Results The expression of BDNF mRNA in the treatment group was higher than that in the model group ( <0.05) . Conclusion Gastrodin can increase some degree of the expression of BDNF.关键词
树鼩/老年痴呆/天麻素/BDNF表达Key words
Tree shrew/Alzheimer's disease/Gastrodin/BDNF expression分类
生物科学引用本文复制引用
何保丽,角建林,李波,李进涛,王丽梅..天麻素对老年痴呆树鼩海马BDNF表达的影响[J].昆明医科大学学报,2013,(9):29-30,37,3.基金项目
云南省高校药学重点实验室项目 （）
