昆明医科大学学报Issue(9)：51-54,4.
糖尿病皮肤缺损愈合进程中单核细胞趋化蛋白-1表达的研究
The Expression of MCP-1 in the Diabetes Mellitus Skin Defect Healing
王少云 1马翔 1张丽 2肖砚斌 1张祥2
作者信息
- 1. 昆明医科大学第三附属医院骨科，云南昆明 650108
- 2. 昆明医科大学基础医学实验教学中心，云南昆明 650500
- 折叠
摘要
Abstract
Objective To study the expression of MCP-1 in the diabetes mellitus skin defect healing, then discuss its effect. Methods The diabetes mellitus models were established, and the expression of MCP-1 was detected by immunohistochemical staining and Elisa. Results The immunohistochemistry stain showed that the expression of MCP-1 in DM group was higher than that in control group at all time. And the serum value of MCP-1 in DM group had statistical significance ( <0.05) at 3 days or 1 week, but that in 2 weeks and 4 weeks was no statistical significance ( <0.05) . Conclusion The MCP-1 might play a role in the healing of diabetes mellitus skin defect through mediate abnormal inflammatory response.关键词
MCP-1/糖尿病皮肤/愈合Key words
MCP-1/The diabetes mellitus skin/Healing分类
医药卫生引用本文复制引用
王少云,马翔,张丽,肖砚斌,张祥..糖尿病皮肤缺损愈合进程中单核细胞趋化蛋白-1表达的研究[J].昆明医科大学学报,2013,(9):51-54,4.
