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279株结核分枝杆菌耐药情况分析

陈连勇 马利 茹浩浩 王金玉 许琳

昆明医科大学学报Issue(1):47-50,4.
昆明医科大学学报Issue(1):47-50,4.

279株结核分枝杆菌耐药情况分析

Analysis on Resistance Status of 279 Strains of Mycobacterium tuberculosis

陈连勇 1马利 1茹浩浩 1王金玉 1许琳1

作者信息

  • 1. 云南省疾病预防控制中心,云南昆明 650022
  • 折叠

摘要

Abstract

Objective The purpose of the study was to understand the resistance status of to anti-tuberculosis drug in Yunnan province, and to provide evidence for tuberculosis (TB) control. Methods The proportional method was used in drug sensitivity test according to the guidelines recommending by WHO. Results Of 301 mycobacterial isolates, 279 (92.7%) strains were complex (MTBC) . The total drug resistance rate was 31.5% (88/279),the initial drug resistance rate of was 27.3%, and the acquired drug resistance rate was 44.3%. The drug resistance rates to INH,RFP,EMB and SM were 19.7%, 10.8%, 12.9%and 19.0%, respectively. The multi-drug resistance (MDR) rate was 9.3%. Conclusion The drug resistant rate of is still high in Yunnan province,and TB control is still a long way to go. Early detection and regular treatment should be done for MDR patients. Drug resistance monitoring as an important part of TB control programs should be regular observation and research.

关键词

结核病/结核分枝杆菌/耐药

Key words

Tuberculosis/Drug resistance

分类

医药卫生

引用本文复制引用

陈连勇,马利,茹浩浩,王金玉,许琳..279株结核分枝杆菌耐药情况分析[J].昆明医科大学学报,2014,(1):47-50,4.

基金项目

卫生部国外贷款办公室世行贷款/英国赠款中国结核病控制项目实施性研究课题 ()

昆明医科大学学报

OACSTPCD

1003-4706

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