中国临床保健杂志Issue(2)：150-152,3.DOI:10.3969/J.issn.1672-6790.2014.02.014
多奈哌齐联合脑蛋白水解物注射液和银杏叶提取物治疗阿尔茨海默病的疗效评价
The effect of donepezil combined with cerebrolysin and ginkgo biloba on alzheimer's disease
王吉 1胡智 1申明达 1翟鑫 1李勇 1杜凯音 1王津 1陈春雷 1张宝和1
作者信息
- 1. 解放军海军总医院干部保健科，北京 100037
- 折叠
摘要
Abstract
Objective To investigate the effect of Donepezil combined with Cerebrolysin(CL)and Ginkgo biloba(Egb76 1 )in the treatment of aged patients with Alzheimer's disease on cognitive function and behavioral disor-ders.Methods A total of 132 patients with Alzheimer's disease were collected and randomly divided into 2 groups:Donepezil combined with Cerebrolysin(CL)and Ginkgo biloba(Egb761)group (combined treatment group,n=66), Donepezil group(n=66).MMSE Scale and ADL Scale of 2 groups were assessed and compared before treatment and 3 months,6 months and 12 months after treatment.Results The cognitive function and behavioral abilities in aged patients with Alzheimer's disease improved markedly (P<0.01 )in the combined group 3 months,6months and 12 months after treatment.Conclusion Combination of Donepezil with Cerebrolysin(CL)and Ginkgo biloba(Egb761 ) can markedly ameliorate the cognitive function and behavioral abilities in patients with Alzheimer's disease with no ob-vious side effects.关键词
阿尔茨海默病/胆碱酯酶抑制剂/银杏素Key words
Alzheimer disease/Cholinesterase inhibitors/Ginkgetin分类
医药卫生引用本文复制引用
王吉,胡智,申明达,翟鑫,李勇,杜凯音,王津,陈春雷,张宝和..多奈哌齐联合脑蛋白水解物注射液和银杏叶提取物治疗阿尔茨海默病的疗效评价[J].中国临床保健杂志,2014,(2):150-152,3.
