皮肤性病诊疗学杂志Issue(6)：392-395,4.DOI:10.3969/j.issn.1674-8468.2013.06.006
樱花提取物的体外抗氧化功能及安全性研究
Anti-oxidative Activity and Safety of Cherry Blossom Extracts in vitro
张云青 1尹颂超 1张赛 2Moonsik CHANG 3唐嘉雯 2关蕾2
作者信息
- 1. 中山大学附属第三医院皮肤科，广东 广州 510630
- 2. 广州莱德璞皮肤研测中心，广东 广州510630
- 3. Natural Solution Company Limited，Gojan-dong，Namdong-gu，Incheon，Republic of Korea
- 折叠
摘要
Abstract
Objective:To study the anti-oxidative activity and safety of Cherry Blossom Extracts in vitro.Methods:The fluorescence in fibroblast cells cultured with different concentrations of Cherry Blossom extract (0.5%、1%、2%) was determined using dichlorodihydrofluorescin diace-tate (DCFH-DA) as fluorescence probe, and the RAW264.7 macrophage cell's livability was de-termined by the MTT assay after cultured with different concentrations of Cherry Blossom extract (0.5%、1%、2%).The fibroblast cells and the RAW264.7 macrophage cell without Cherry Blos-som extract was studied as controls respectively .Results:The fluorescence in fibroblast cells cul-tured with different concentrations Cherry Blossom extract was lower than the control group .The fluorescence of 0.5%、1%、2% Cherry Blossom extract group decreased by 16.55%, 19.19%and 29.3%respectively ( all P<0.05 ) at 90 min compared with the control group .Meanwhile , MTT experiments showed that after cultured with different concentrations of Cherry Blossom extract (0.5%, 1%, 2%) , the RAW 264.7 macrophage cell viability was 100.27%, 98.93% and 100.53%respectively .Conclusion:Cherry Blossom extract has anti-oxidation function ,and has no toxic effects to the RAW 264 .7 macrophages cell .关键词
樱花/抗氧化/抗衰老Key words
Cherry blossom/Anti-oxidation/Anti-aging分类
生物科学引用本文复制引用
张云青,尹颂超,张赛,Moonsik CHANG,唐嘉雯,关蕾..樱花提取物的体外抗氧化功能及安全性研究[J].皮肤性病诊疗学杂志,2013,(6):392-395,4.
