岭南现代临床外科Issue(2)：143-146,4.DOI:10.3969/j.issn.1009-976X.2014.02.008
糖链抗原724、癌胚抗原在结直肠癌术后患者血清中的表达及相关性研究
Postoperative carbohydrate antigen 724 (CA724) and CEA expressions as prognostic factors in patients with colorectal cancer
摘要
Abstract
Objective To detect the serum carbohydrate antigen 724 (CA724) and embryonic antigen (CEA) expression levels in colorectal cancer patients and observe the correlation between both of them. Methods Thirty-eight colorectal cancer patients as observer group; and 38 patients without recurrence or metastasis of cancer as control group. After taking the fasting blood , the serum levels of CA724 and CEA were detected using electrochemiluminescence method. Besides , the correlation of CA724 with CEA was tested using Pearson correlation coefficient. Results The serum levels of CA724 and CEA were higher in colorectal cancer patients than those in the control group. And the differences were statistically significant (P<0.01). In 76 patients, the serum levels of CA724 and CEA were significantly correlated, (correlation coefficient r=0.622, P<0.01). Conclusion CA724 and CEA are significantly increased in the serum of advanced colorectal cancer patients. .And the serum level of CA724 is significantly correlated with the serum level of CEA in colorectal cancer patients. .CA724 as an follow-up indicator of colorectal cancer after operation of is worthy of further study.关键词
肿瘤标志物/糖链抗原724/癌胚抗原/结直肠癌/随访Key words
Tumor markers/Carbohydrate antigen 724/Carcinoembryonic antigen/Colorectal cancer/Follow-up分类
医药卫生引用本文复制引用
李国文,曾山崎,王成兴,李莉珊,叶华,杨平..糖链抗原724、癌胚抗原在结直肠癌术后患者血清中的表达及相关性研究[J].岭南现代临床外科,2014,(2):143-146,4.基金项目
广州市科技计划项目 （）
