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扶肾泄浊法对维持性血液透析患者微炎症状态的影响

张琼 胡琼丹 李小军 陈定国 梁颖兰 许艳文

泸州医学院学报Issue(5):462-465,4.
泸州医学院学报Issue(5):462-465,4.DOI:10.3969/j.issn.1000-2669.2013.05.011

扶肾泄浊法对维持性血液透析患者微炎症状态的影响

The effects of Fushen Xiezhuo therapy on microinflammatory state in maintenance hemodialytic patients

张琼 1胡琼丹 1李小军 1陈定国 1梁颖兰 1许艳文1

作者信息

  • 1. 泸州医学院附属中医医院肾病内科 四川泸州 646000
  • 折叠

摘要

Abstract

Objective: To observe the effects of Fushen Xiezhuo therapy (by means of Shenxiankang Granules)on nutritional and microinflammatory state in maintenance hemodialytic patients. Methods: 40 Patients with maintained hemodialysis were randomized into treatment group , treated with Shenxiankang Granules plus general treatment,and the control group only received general treatment. 3 months later, the weight, AMC, Alb,PA,TC,TG,HDL-C, LDL-C,Hb, CRP,TNF-α and IL-6 were checked. Results: In treatment group ,dry body weight,MAMC,Alb,PA and Hb were significantly increased after treatment (P<0.05),while the levels of CRP,TNF- α and IL-6 were decreased (P< 0.05). Dry body weight, MAMC, Alb, PA and Hb of treatment group were signifcantly higher (P< 0.05),while the levels of CRP, TNF- α and IL-6 were lower than those of control group (P< 0.05). After treatment, the levels of TC,TG, HDL-C and LDL-C had no significant change in both groups (P﹥0.05). In control group, levels of CRP,TNF- α and IL-6 were higher after treatment, but without statistical significance. Conclusion: Fushen Xiezhuo therapy can improve the maintenance hemodialytic patients' nutritional and microinflammatory state, and can reduce the incidence of cardiovascular events through stimulating appetite and inhibiting the production of CRP,IL-6 and TNF-α.

关键词

扶肾泄浊/微炎症/维持性血液透析

Key words

Fushen Xiezhuo therapy/Microinflammatory state/Maintenance hemodialysis

分类

医药卫生

引用本文复制引用

张琼,胡琼丹,李小军,陈定国,梁颖兰,许艳文..扶肾泄浊法对维持性血液透析患者微炎症状态的影响[J].泸州医学院学报,2013,(5):462-465,4.

基金项目

泸州市科技局课题 ()

泸州医学院学报

2096-3351

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