国际眼科杂志Issue(1)：56-58,3.DOI:10.3980/j.issn.1672-5123.2014.01.15
MicroRNAs 在晶状体中的功能
Functions of MicroRNAs in lens
摘要
Abstract
MicroRNAs ( miRNAs) are a class of single-stranded, small non-coding RNAs with 21 to 23 nucleotides, which can promote the degradation of mRNA or suppress their translation to regulate the expression of target gene through their incomplete combination with non-coding region at 3'terminal of target mRNAs.miRNAs are widely involved in the physiological and pathological processes in vivo and affect the cell development, the processes of diseases by changing their expression levels.In recent years, more researchers have found that miRNAs are identified widely and specifically in eyes including the lens, retina and cornea and their abnormal expressions may be associated with some eye diseases.This review summarizes the current information about expressions and functions of miRNAs in the lens, in order to seek for new targets for the clinical diagnosis and treatment of the lens opacity.关键词
MicroRNAs/晶状体/白内障Key words
microRNAs/lens/cataract引用本文复制引用
陶海波,贾音,高谦,李闻捷..MicroRNAs 在晶状体中的功能[J].国际眼科杂志,2014,(1):56-58,3.基金项目
中国国家自然科学基金（面上项目）（ No．81170834）@@@@National Natural Science Foundation of China （）
