国际眼科杂志Issue(2)：365-367,3.DOI:10.3980/j.issn.1672-5123.2014.02.50
Bcl-2和 Bax 在结膜松弛症患者结膜组织中的表达
Expression of Bcl -2 and Bax of conjunctivochalasis patients
摘要
Abstract
AIM: To study expression of Bcl -2 and Bax in conjunctival tissue samples of conjunctivochalasis patients. <br> METHODS:To observe the histopathological change of conjunctivochalasis by HE staining of conjunctival tissue. Immunohistochemical staining was applied to compare the expression situation of Bcl-2 and Bax in conjunctival tissue of conjunctivochalasis patient ( 20 samples ) and the normal conjunctiva tissue (10 samples). <br> RESULTS: There were lymphocyte and plasmocyte infiltration in the conjunctivochalasis tissue. The expression of Bcl -2 in the conjunctivochalasis was similar with the normal conjunctiva tissue (P>0.05).The expression of Bax in the two tissues showed significant difference (P<0.05).Spearman rank correlation analysis ( r =0.432, P >0.05 ) indicated that there was no correlation between the expression of Bcl-2 and Bax. <br> CONCLUSION: Unbalanced expression of Bcl-2 and Bax in conjunctival tissue may play a significant role in the occurrence and development of conjunctivochalasis.关键词
结膜松弛症/免疫组织化学/Bcl-2/BaxKey words
conjunctivochalasis/immunohistochemistry/Bcl-2/Bax引用本文复制引用
董利群,刘鸫,张兴儒..Bcl-2和 Bax 在结膜松弛症患者结膜组织中的表达[J].国际眼科杂志,2014,(2):365-367,3.基金项目
上海市嘉定区科委基金（ No．2010023）基金项目上海市嘉定区科委基金（ No．2010023）@@@@Science and Technology Commission of Jiading District， Shanghai （）
