国际眼科杂志Issue(3)：457-459,3.DOI:10.3980/j.issn.1672-5123.2014.03.20
CCR3在湿性年龄相关性黄斑变性中的研究进展
Study progress of CCR3 in wet age -related macular degeneration
吴宪巍 1刘哲丽2
作者信息
- 1. 117000 中国辽宁省本溪市中心医院眼科
- 2. 110000 中国辽宁省沈阳市，中国医科大学附属第一医院眼科
- 折叠
摘要
Abstract
According to the study, chemokine receptor 3 ( CCR3 ) in the eye is mainly distributed in retinal pigment epithelial cells, and also expressed in the choroidal vascular endothelial cells ( CECs ) . The specificity of CCR3's high expression in wet age -related macular degeneration ( AMD) was found, and it is proved that in wet-AMD patients, it plays an important role in the formation of choroidal neovascularization ( CNV) .In this paper, the structure, function, the problem of current research and the future direction of CCR3 were summarized.It is believed that with the further research on CCR3, it will not only help us to find a new method of wet-AMD diagnosis and treatment, but also may provide an important reference for other CNV disease research and new anti-CNV drugs.关键词
湿性年龄相关性黄斑变性/受体/趋化因子受体3Key words
wet age-related macular degeneration/receptor/chemokine receptor 3引用本文复制引用
吴宪巍,刘哲丽..CCR3在湿性年龄相关性黄斑变性中的研究进展[J].国际眼科杂志,2014,(3):457-459,3.
