国际眼科杂志Issue(3)：464-467,4.DOI:10.3980/j.issn.1672-5123.2014.03.22
视网膜色素上皮发育发生学的研究进展
Recent advances of morphogenesis and development in retinal pigment epithelium
张燕 1彭绍民2
作者信息
- 1. 022150 中国内蒙古自治区牙克石市，内蒙古林业总医院眼科
- 2. 150000 中国黑龙江省哈尔滨市，哈尔滨医科大学附属第二医院眼科
- 折叠
摘要
Abstract
The retinal pigment epithelium ( RPE ) is a pigmented simplecuboidal monolayer of epithelial cells that located between the photoreceptors in the neural retina and the Bruch's membrane in the vascular choroid and is critical for the survival and function of retinal photoreceptors. The pathogenesis of multiple congenital RPE diseases is closely related to embryonic development.This review summarized the current knowledge of the molecular mechanisms controlling early steps of RPE development, with emphasis on basic process, critical signaling molecules, key transcription factors and pathway maintaining the RPE cell fate.关键词
视网膜色素上皮/发育Key words
retinal pigment epithelium/development引用本文复制引用
张燕,彭绍民..视网膜色素上皮发育发生学的研究进展[J].国际眼科杂志,2014,(3):464-467,4.
