摘要
Abstract
Primary open angle glaucoma ( POAG ) is the main cause of blindness with visual field damage and optic nerve degeneration.In recent years, a lot of researches have been done, showing that genetic factors and gene mutation play an important role in POAG.There are more than 20 related POAG genes. Now we will review the related genes of POAG, especially the well known causative genes of MYOC, OPTN, WDR36, and CAV1/CAV2, in terms of their locations, structures, research progress, et al, and provide a reference for genetic research in primary open-angle glaucoma.关键词
原发性开角型青光眼/基因变异/遗传/研究进展Key words
primary open angle glaucoma/gene mutation/heredity/research progress
