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复方樟柳碱注射液治疗中心凹旁型中浆病

徐建锋 陈开聪

国际眼科杂志Issue(4):701-703,3.
国际眼科杂志Issue(4):701-703,3.DOI:10.3980/j.issn.1672-5123.2014.04.36

复方樟柳碱注射液治疗中心凹旁型中浆病

Treatment of juxtafoveal central serous chorioretinopathy by compound anisodine injection

徐建锋 1陈开聪1

作者信息

  • 1. 362000 中国福建省泉州市,解放军第180医院眼科医院
  • 折叠

摘要

Abstract

AIM: To investigate the efficiency and security of compound anisodine injection in the treatment of juxtafoveal central serous chorioretinopathy ( CSC) . <br> METHODS: Sixty patients ( 60 eyes ) who were diagnosed of juxtafoveal CSC were assigned randomly into 2 groups:32 cases (32 eyes, therapeutic group) were injected subcutaneously compound anisodine injection for 2mL q.d around superficial temporal arteries in the affected eyes;28 cases (28 eyes, control group) received only traditional oral medication. Both groups received therapy for 2 to 4 courses of treatment. The main observations were the best corrected visual acuity ( BCVA) , subjective symptom, visual field, average light sensitivity and optical coherent topography ( OCT) . <br> RESULTS: There was no significant difference between the therapeutic group and the control group before treatment (P>0.05), but all the outcome measures at 1, 3mo in the treatment group were significantly improved as compared with control group ( P<0.05).After 6mo, there were no significant difference between the two groups in all measures ( P>0.05 ).No severe adverse reaction was noted except mild ones such as temporary dry mouth, dizziness and palpitation in a few cases. <br> CONCLUSION: Compound anisodine injection has remarkable effects in the treatment of juxtafoveal CSC.It can shorten the course, improved the visual function and&nbsp;decreased the recurrence rate of CSC.

关键词

复方樟柳碱注射液/中心性浆液性脉络膜视网膜病变/中心凹旁/疗效/安全

Key words

compound anisodine injection/central serous chorioretinopathy/juxtafoveal/efficiency/safety

引用本文复制引用

徐建锋,陈开聪..复方樟柳碱注射液治疗中心凹旁型中浆病[J].国际眼科杂志,2014,(4):701-703,3.

国际眼科杂志

OACSTPCD

1672-5123

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