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MMP-9与糖尿病视网膜病变患者血清中果糖胺的关联性

王冲 王艳丽 蔡安季 任亚琳

国际眼科杂志Issue(5):950-951,2.
国际眼科杂志Issue(5):950-951,2.DOI:10.3980/j.issn.1672-5123.2014.05.51

MMP-9与糖尿病视网膜病变患者血清中果糖胺的关联性

Study of the relationship of MMP-9 and serum fructosamine levels in diabetic retinopathy patients

王冲 1王艳丽 2蔡安季 2任亚琳2

作者信息

  • 1. 518600 中国广东省深圳市南山区妇幼保健院眼科
  • 2. 518600 中国广东省深圳市,广东医学院附属南山医院眼科
  • 折叠

摘要

Abstract

AIM:To explore the relationship of MMP-9 and serum fructosamine levels and further illustrate the role of the development in diabetic retinopathy patients. <br> METHODS: Serum MMP - 9 levels were measured using enzyme - linkedimmunosorbent assays a in 30 health controls and 30 diabetic retinopathy patients, the relationship of MMP-9 and serum fructosamine levels were analyzed. <br> RESULTS: Compared with healthy controls. The expression levels of MMP - 9 indiabetic retinopathy patients were significantly increased [(8. 14±2. 28pmol/L), vs ( 2. 47 ± 1. 41pmol/L )], MMP - 9 were positive correlation with fructosamine (r=0. 94, P<0. 05). <br> CONCLUSION:The occurrence and progress of diabetic retinopathy might be closely related to the expression level of MMP-9, and the abnormal expression of MMP-9 in patients'serum might be associated with the secretion of fructosamine.

关键词

MMP-9/糖尿病视网膜病变/果糖胺

Key words

MMP-9/diabetic retinopathy/fructosamine

引用本文复制引用

王冲,王艳丽,蔡安季,任亚琳..MMP-9与糖尿病视网膜病变患者血清中果糖胺的关联性[J].国际眼科杂志,2014,(5):950-951,2.

国际眼科杂志

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1672-5123

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