南华大学学报（自然科学版）Issue(4)：82-85,4.
2,2'-联咪唑并[5,6-f]邻菲罗啉及其铜配合物的合成
The Synthesis of 2,2’-bisglyoxaline[5,6-f] phenanthroline and its Copper Complexes
摘要
Abstract
The metal complexes of phenanthroline ramification can bind to DNA through noncovalent interactions,which will help develop new anticancer drugs. 1,10-phenanthro-line-5,6-dione (DIONE) was synthesized by oxidation of 1,10-Phenanthroline. 2,2’-bisg-lyoxaline[5,6-f]phenanthroline (BGP) was then obtained by heating the mixture of DI-ONE / 2-imidazolecarboxaldehyde / ammonium acetate and glacial acetic acid to reflux. At last,copper complex of BGP was obtained by coordination reaction,which was BGP charac-terized by IR,and all products were characterized by elemental analysis,NMR spectroscopy and IR. The target product may have activity on DNA.关键词
1 ,10-邻菲罗啉-5 ,6-二酮/2-醛基咪唑/合成/配合物Key words
1,10-phenanthroline-5,6-dione/2-imidazolecarboxaldehyde/synthesis/complex分类
化学化工引用本文复制引用
孙允凯,阳鹏飞,梁俊,陈民..2,2'-联咪唑并[5,6-f]邻菲罗啉及其铜配合物的合成[J].南华大学学报（自然科学版）,2013,(4):82-85,4.基金项目
国家自然科学基金资助项目(11305086) （11305086）
博士启动基金资助项目(2011XQD55) （2011XQD55）
