畜牧与饲料科学Issue(12)：5-8,4.
外源褪黑激素（MT）对内蒙古绒山羊皮肤中BMP2基因表达的影响
Effects of Exogenous Melatonin on the Gene Expression of BMP2 in the Skin of Inner Mongolia Cashmere Goat
摘要
Abstract
The aim of this study was to investigate the expression laws of bone morphogenetic protein 2 (BMP2)gene in the development skin hair follicles of Inner Mongolia Cashmere Goat in a complete period and the effects of implanting melatonin (MT)on its expression. Eight female mature Inner Mongolia Cashmere Goats were randomly divided into 4 groups. MT in group 1-3 was implanted in animals (test groups) and the fourth group in which MT was not implanted was control group. The samples of skin from lateral part were collected during one year to detect the expression of BMP2 gene in developmental stage of hair follicles by real-time quantitative PCR. The results showed that the expression amount of BMP2 gene in prosperous period and resting period of hair follicle′s development was slowly increased and the expression amount in resting period was higher than that in growing period. The expression amount of BMP2 gene in resting period was reduced after implanting MT and there was no significant difference of the expression amount during the whole growth period. The expression amount of BMP2 in the skin of Inner Mongolia Cashmere Goat was closely related with the periodic growth of hair follicles. The expression model of BMP2 gene in the growth period of hair follicles was changed after implanting MT. It was speculated that BMP2 gene might be involved in regulating the growth and development of skin hair follicles in Inner Mongolia Cashmere Goat.关键词
BMP2基因/褪黑激素/皮肤/毛囊/内蒙古绒山羊Key words
BMP2 gene/melatonin/skin/hair follicle/Inner Mongolia Cashmere Goat分类
农业科技引用本文复制引用
苏蕊,丽春,杨钟,张燕军,赵艳红,王瑞军,刘志红,张文广,李金泉..外源褪黑激素（MT）对内蒙古绒山羊皮肤中BMP2基因表达的影响[J].畜牧与饲料科学,2013,(12):5-8,4.基金项目
内蒙古自治区自然科学基金项目（2011BS0407）；内蒙古农业大学博士科研启动基金项目（BJ07-50）；国家绒毛用羊产业技术体系项目（nycytx-40-8）；内蒙古民族大学科学研究项目（NMD1214）。 （）
