摘要
Abstract
Objective To explore relationship among clinicopathological factors in Luminal subtype breast cancer. Meth-ods The data of 145 female patients with Luminal subtype breast cancer were collected retrospectively. Their relationship with bi-omarkers, such as ER, PR, HER2, P53, age, stage of TNM was analyzed. Results Tumor size was positively related with me-tastasis of lymph node. The correlation between expression of ER and PR was statistically significant(r=0. 469, P=0. 000). The expression of HER2 was negatively related with age(r= -0. 197, P =0. 017). Conclusion The opportunity of metastasis of lymph node in large tumor is higher than in little tumor. The expression of ER and PR is coactions in breast cancer. The HER2 is more likely over expression in younger patient with breast cancer. PR and HER2 play important role in treatment of Luminal sub-type breast cancer, and need to be examined exactly.关键词
Luminal亚型/乳腺癌/临床病理因子Key words
luminal subtype/breast cancer/clinicopathological factors分类
医药卫生
