四川医学Issue(4)：450-451,2.
慢性阻塞性肺病急性加重期患者血清中IL-32、CRP的变化及其意义
Clinical Efficacy of the Changes of Serum IL-32 and CRP in Patients with Acute Exacerbation of Chronic Obstruc-tive Pulmonary Disease
范世明 1郝青林 2任燕1
作者信息
- 1. 宜宾市第一人民医院呼吸内科，儿科，四川 宜宾644000
- 2. 昆明医科大学第一附属医院呼吸内一科，云南 昆明650032
- 折叠
摘要
Abstract
Objective To study the implication of interleukin-32(IL-32)and C-reactive protein(CRP)in the exacerbation of chronic obstructive pulmonary diseases(AECOPD). Methods The serum was sampled and prepared from 33 cases of COPD patients with acute exacerbation before and after two weeks therapy and 20 normal controls. Serum level of IL-32 was detected by ELISA and CRP by immunoturbidimetry method. Results The level of IL-32 in AECOPD Is significantly higher than that after therapy(P<0. 05)and lower than that in control group(P<0. 05). The level of CRP in acute exacerbation is significantly higher than that in control group(P<0. 05). Conclusion IL-32 and CRP are involved in the acute inflammation in COPD which may be indices of infection in COPD patients.关键词
慢性阻塞性肺疾病急性加重期/白细胞介素-32/C反应蛋白Key words
the exacerbation of chronic obstructive pulmonary diseases/Interleukin-32/C-reactive protein分类
医药卫生引用本文复制引用
范世明,郝青林,任燕..慢性阻塞性肺病急性加重期患者血清中IL-32、CRP的变化及其意义[J].四川医学,2014,(4):450-451,2.
