摘要
Abstract
Objective To observe the effect of acute coronary syndrome ( ACS) clinical efficacy and safety of early appli-cation of different doses of atorvastatin. Methods the clinical diagnosis of acute coronary syndrome patients with a total of 80 ca-ses, were randomly divided into 10mg group and 40m group, nightly medication time, blood lipid and high sensitive C- reactive protein in 4 weeks, 12 weeks ( hsCRP) , the incidence of adverse reactions and cardiac events were followed up for 3 months the. Results ①Two groups after 4 weeks, 12 weeks of total cholesterol, low density lipoprotein, the level of hsCRp 40 mg in group mg than in group mg decreased more significantly in 10 mg, there was significant difference between two groups (P<0. 05). ②The two groups had no serious adverse reactions. Conclusion Acute coronary syndrome (ACS) 40m g early application atorvas-tatin can effectively reduce the total cholesterol ( TC) and low density lipoprotein cholesterol ( LDL-C) levels, reduce inflammatory factors, and has a good safety.关键词
急性冠状动脉综合征/阿托伐他汀/强化降脂/安全性Key words
acute coronary artery syndrome/atorvastatin/intensive lipid-lowering/safety分类
医药卫生
