摘要
Abstract
Objective:To explore the changes of liver tissue pathology of ALT <2 ULN Chronic HBV inflected persons and the relation of the changes , liver biochemistry and fibrosis index .Methods:102 cases between the two groups of ALT <2 ULN chronic HBV inflected patients were examined of their percutaneous transhepatic puncture biopsy , judge their liver tissue inflammation and necrosis grade and the degree of fibrosis staging .According to pathological grading and staging , the patients were divided into G 0~1、G2、G3~4 group and S0~1、S2、S3~4 group, and compare the difference of liver biochemistry and fibrosis indexes .Results:Among 102 patients, 60 patients'inflammation and necrosis grading≥G2 (58.82%),55 patients'degree of fibrosis staging≥S2 (53.92%).According to the different in-flammation and necrosis grading and degree of fibrosis staging , each group's liver biochemical indexes level was compared , there were no significant differences (P>0.05);PCⅢand HA of G 0~1 group and G2 group were lower than G3~4 group, PCⅢand HA of S0~1 group and S2 group were lower than S3~4 group, there were significant differences (P<0.05).Conclusion:Liver biochemical indexes cannot reflect the severity of liver disease of ALT <2 ULN Chronic HBV inflected persons , PCⅢand HA had important reference value , needle biopsy of liver is still the best standard to judge inflammation of the liver and the degree of fibrosis .关键词
肝炎/乙型/慢性/肝组织/病理学Key words
Hepatitis B/Chronic/Hepatic tissue/Pathology分类
医药卫生
