摘要
Abstract
Objective:To explore the methoxy polyethylene glycol -benzotriazole ( mPEG-BTC) erythrocyte antigens in vitro modifi-cation troubleshoot crossmatch role .Methods:The modified with mPEG -BTC 12 healthy blood donors and 14 cases of red blood cells cross matching blood samples erythrocyte difficult to observe mPEG -BTC for healthy donors erythrocyte blood group antigen masking effect, compared mPEG-BTC healthy blood donors before and after modification red blood cells and difficult cross matching blood sam -ples with blood results and comparison with clinical results with blood .Results:mPEG -BTC fully shielded healthy donors erythrocyte blood group antigens , modified erythrocytes and difficult cross matching blood samples did not appear agglutination , difficult cross-matc-hing of blood samples modified with mPEG -BTC red blood cross matching consistency was higher than clinical cases with blood (P <0. 05).Conclusion:mPEG-BTC vitro modified red blood cell antigens could effectively solve the difficult problem of cross -matching of blood, worthy of promotion .关键词
mPEG-BTC/修饰抗原/红细胞/交叉配血Key words
mPEG-BTC/Modified antigen/Erythrocytes/Crossmatch分类
医药卫生
