山西中医学院学报Issue(5)：19-20,23,3.
啤酒花对朱砂莲所致马兜铃酸肾病的拮抗作用
Antagonism of Hops to Renal Toxicity Induced by Radix Aristolochiae Kaempferi
摘要
Abstract
Objective:To observe antagonism of hops to the renal toxicity induced by Radix aristolochiae kaempferi. Method:120 SD rats were randomly divided into blank group;large,medium and small dosage of Radix aristolochiae kaempferi groups;large,medium and small dosage of Radix aristolochiae kaempferi combined with dry hops groups and large,medium and small dosage of Radix aristolochiae kaempferi combined with fresh beer groups.The rats in blank group were taken isometric physiological saline,the rats in other groups were administrated by corresponding medicine,for 60 days successively. AKP,Scr,LYS,β2-microglobulin biochemical indexes were examined. Result:Compared with high dosage of Radix aristolochiae kaempferi group,contents of AKP、Scr、β2-MG、LYS were decreased in Radix aristolochiae kaempferi combined with dry hops groups;β2-microglobulin biochemical was decreased in large,medium dosage of Radix aristolochiae kaempferi combined with fresh beer groups (P<0.05). AKP was lower in large,medium,small dosage of Radix aristolochiae kaempferi combined with fresh beer groups than that in high dosage of Radix aristolochiae kaempferi group. Conclusion:Hops can alleviate the renal toxicity of Radix aristolochiae kaempferi in a certain extent.关键词
啤酒花/朱砂莲/肾毒性/拮抗Key words
hops/Radix aristolochiae kaempferi/renal toxicity/antagonism分类
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庞俊伟..啤酒花对朱砂莲所致马兜铃酸肾病的拮抗作用[J].山西中医学院学报,2013,(5):19-20,23,3.
