摘要
Abstract
a.Methods:Eighty eight middle and old aged patients with insomnia were included in the study and randomly divided into the treatment group (group A, n=40) and control group (group B, n=36).The two groups were given Anshenbunao liquid and estazolam treatment respectively.Patients were evaluated with AIS score before treatment and at the end of the first , second and third course of treatment . According to AIS scores before treatment they were divided into mild insomnia group ( group A1, n=28;group B1, n=25) and severe insomnia group (group A2, n=12;group B2, n=11).The reducing rate of total AIS score was used for judging the therapeutic effica-cy.Adverse reactions were recorded during the treatment .Routine inspections were made during each evaluation .Results:The total ef-fective rate had no statistical significance between group A and group B or between group A 1 and group B1 after treatment.The total ef-fective rate in group A2 at the end of the second and third course of treatment were significantly lower than those of group B 2 (χ2 =6. 13, P=0.01;χ2 =4.54, P=0.03).The AIS scores after treatment were significantly lower than those before the treatment in group A and B and subgroups (P<0.05).The AIS score in group B2 was lower than group A2 after the third couse of treatment (t=2.105, P=0.047).The adverse reactions during the treatment in group A was less than group B .Conclusion:Anshenbunao liquid can be used in the treatment of patients with insomnia , especially for those with mild insomnia and the curative effect is similar with estazolam .It is worth of clinical application.关键词
安神补脑液/舒乐安定/失眠症/疗效Key words
Anshenbunao liquid/Estazolam/Insomnia/Curative effect
