世界中医药Issue(12)：1404-1406,3.DOI:10.3969/j.issn.1673-7202.2013.12.007
丹参酮ⅡA 磺酸钠注射液与冠心病炎症因子的研究进展
Sodium Tanshinone IIA Sulfonate Injection and Inflammatory Factors of Coronary Heart Diseases
摘要
Abstract
A large number of basic and clinical studies have demonstrated that inflammation plays a vital role in atherosclerosis forma -tion and evolution .Inflammation factors stimulate the formation and rupture of unstable coronary atherosclerotic plaque .Then the throm-bosis formed is the main reason of most acute coronary syndromes (ACS).Sodium tanshinone IIA sulfonate(STS) is applied for Coro-nary Heart Disease ( CHD) which can improve blood circulation and inhibit inflammation .This paper reviewed on the relevance between STS and CHD related inflammatory factors including C-reactive protein (CRP),homocysteine(Hcy),Tumor necrosis factor-α(TNF -α),Human leukocyte differentiation antigen 40 (CD40),fibrinogen(Fib),interleukin-6(IL-6),matrix metal loprotoinases (MMPs),nu-clear factor-кB( NF-кB) ,so as to explore specific links of STS ’ s affection in inflammatory factors with CHD to provide curing reference in the future .关键词
冠心病/丹参酮IIA磺酸钠注射液/炎症因子Key words
Coronary Heart Disease ( CHD)/Sodium tanshinone IIA sulfonate injection ( STS)/Inflammatory factor引用本文复制引用
焦阳,李思铭,高铸烨,徐浩..丹参酮ⅡA 磺酸钠注射液与冠心病炎症因子的研究进展[J].世界中医药,2013,(12):1404-1406,3.基金项目
国家自然科学基金 （）
