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药性理论指导的附子配伍减毒试验研究

张广平 朱晓光 杨海润 张思玉 叶祖光

世界中医药Issue(2):129-131,3.
世界中医药Issue(2):129-131,3.DOI:10.3969/j.issn.1673-7202.2014.02.001

药性理论指导的附子配伍减毒试验研究

Research on Reducing Fuzi’ toxicity under Guidance of Theory of Medicinal Nature

张广平 1朱晓光 1杨海润 1张思玉 1叶祖光2

作者信息

  • 1. 中药复方新药开发国家工程研究中心,北京,100075
  • 2. 中国中医科学院,北京,100700
  • 折叠

摘要

Abstract

Objective:In accordance with the theory of medicinal nature , we explored new ways of reducing toxicity of Fuzing by combi-ning it with other medicinal herbs .Methods:By conducting toxicological experiments ( acute toxicity in combination with cardiac toxici-ty), we tested four combination theories , i.e.using cold medicinal to inhibit hot medicinal , using sweet medicinal to relieve toxicity , u-sing soft medicinal to curb tough medicinal , modifying toxicity.Results:Compared with combining with medicinal of sweet , or soft, or modifying nature, the combination with cold medicinal proved to be most significant at reducing Fuzi ’ toxicity.Conclusion:The theory of medicinal nature provides a new thinking and method to reduce Chinese medicine ’s toxicity.

关键词

药性理论/配伍减毒/附子

Key words

Theory of medicinal nature/Reducing toxicity by medicinal combination/Fuzi

分类

医药卫生

引用本文复制引用

张广平,朱晓光,杨海润,张思玉,叶祖光..药性理论指导的附子配伍减毒试验研究[J].世界中医药,2014,(2):129-131,3.

基金项目

国家重点基础研究发展计划(973计划)课题有毒中药配伍减毒原理和方法学研究 ()

世界中医药

OACHSSCDCSTPCD

1673-7202

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