世界中医药Issue(2)：237-241,5.DOI:10.3969/j.issn.1673-7202.2014.02.031
芪苈强心胶囊治疗慢性心力衰竭疗效分析
A Systematic Review on The Effects of Qili Qiangxin Capsule Treating Chronic Heart Failure
摘要
Abstract
Objective:To systematically review the effects of Qili Qiangxin capsule treating chronic heart failure .Methods:Clinical trials on Qili Qiangxin capsules treating chronic heart failure ( CHF) published during 2008 and September 2013 were searched from the follow-ing electronic databases including Cochrane Library , Embase, PubMed, CNKI, CBM, Wanfang, VIP.Altogether 28 studies including 2536 patients were included in the review , and the data were analyzed by using Review Manager 5.0.Results:Qili Qiangxin capsule can improve the prognosis of chronic heart failure .Meta-analysis results showed that , 1) Reducing the levels of N-terminal Pro of Pro-brain natriuretic peptide (NT-pro BNP) and brain natriuretic peptide(BNP):the level of NT-pro BNP of the treatment group was lower than that of the control group [SMD=-1.57,95%CI(-1.79,-1.34),P<0.000 01],the level of BNP in treatment was lower than that of the control group [SMD=-0.60,95%CI(-0.77,-0.43),P<0.000 01];2) Treatment group better improved cardiac function NYHA [OR=3.48.95%CI(2.66,4.55),P<0.000 01];3) The distance of 6-minute walking test was longer in treatment group [SMD=1.03,95%CI(0.91,1.16),P<0.000 01];4) Treatment group better improved the left ventricular ejection fraction [SMD=1.06,95%CI(0.96,1.16),P<0.000 01];5) The incidence of adverse reactions was lower in treatment group [OR=0.23.95%CI (0.11,0.47),P<0.000 01].Conclusion:Qili Qiangxin Capsule can obviously improve the cardiac function and the quality of life of patients with chronic heart failure , and it is safe and effective .关键词
芪苈强心胶囊/慢性心力衰竭/Meta分析Key words
Exercise-based cardiac rehabilitation/Coronary heart disease/Chronic heart failure/Meta-analysis分类
医药卫生引用本文复制引用
徐宁,唐海沁,张亚文..芪苈强心胶囊治疗慢性心力衰竭疗效分析[J].世界中医药,2014,(2):237-241,5.基金项目
安徽省卫生厅基层慢病防治科技项目 （）
