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肺与大肠 LPS 信号通路相关性的实验研究

刘絮 刘晓燕 郭霞珍

世界中医药Issue(4):422-423,426,3.
世界中医药Issue(4):422-423,426,3.DOI:10.3969/j.issn.1673-7202.2014.04.007

肺与大肠 LPS 信号通路相关性的实验研究

The Experiment al Study on LPS Signal Path Correlation of Lung and Large Intestine

刘絮 1刘晓燕 1郭霞珍1

作者信息

  • 1. 北京中医药大学,北京,100029
  • 折叠

摘要

Abstract

Objective:To study LPS signal path changes of lung and large intestine .Methods:Mice were randomly divided into physio-logical group , hyperoxia group , hypoxia group , diet restriction group , water restriction group .The LPS signal path ’ s correlation of lung and large intestine was observed detecting changes of variation of TLR 4, MD2 and CD14 in lung and large intestine .Results: When TLR4 and MD2 in the lungs of hyperoxia group and hypoxia group increased , they also increased in the large intestines .When TLR4 and MD2 in the large intestines of diet restriction group and water restriction group increased , they also increased in the lungs .Conclusion:Lung and large intestine can be thought to have related synergy identification in TLR 4 and MD2 of LPS signal path .

关键词

肺与大肠/LPS/TLR4/MD2/CD14

Key words

Lung and large intestine/LPS/TLR4/MD2/CD14

分类

医药卫生

引用本文复制引用

刘絮,刘晓燕,郭霞珍..肺与大肠 LPS 信号通路相关性的实验研究[J].世界中医药,2014,(4):422-423,426,3.

基金项目

国家重点基础研究发展计划(973计划)项目 ()

世界中医药

OACHSSCDCSTPCD

1673-7202

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