世界中医药Issue(4)：475-481,7.DOI:10.3969/j.issn.1673-7202.2014.04.025
针刺对骨骼肌急性钝挫伤模型形态学影响的实验观察
Observation on Experiment of the Morphological Effects of Acupuncture on Acute Blunt Skeletal Muscle Contusion Model
摘要
Abstract
Objective:To observe the morphological effects of acupuncture on Ashi points of rabbits with acute gastrocnemius blunt con -tusion.Methods:Modeling was given on gastrocnemius muscle in rabits'hindquarter by using method of free falling with quantitative load to duplicate acute skeletal muscle injury .The swelling degree and hardness of gastrocnemius ( immediately, 24hours, 48hours after building the model) was measured.Materials were taken 48hours after building the model.The content of CK and LDH in serum were tested.The morphological changes of gastrocnemius under light microscope and electron microscope were observed .Results:48 hours after building the model , the content of CK of model group , acupuncture group , CsA model group and CsA acupuncture group increased significantly compared the nature group (P<0.05);compared with the nature group, differences of the content of LDH of model group and CsA model group increased significantly ( P<0.05 ); compared with the model group , acupuncture group , CsA model group and CsA acupuncture group decreased significantly ( P<0.05 ) .Under light microscope , different kinds of muscle fiber trauma could be found in all groups except the nature group .Under electron microscope , Ultrastructural changes could be seen in all groups except the nature group .Conclusion:The modeling method can successfully copy acute closed skeletal gastrocnemius muscle injury model .Acu-puncture could promote the reparative process of acute blunt muscle effectively , while CsA would partially reduce the repairing effect of acupuncture .关键词
针刺/骨骼肌/形态学Key words
Acupuncture/Skeletal muscle/Morphology分类
医药卫生引用本文复制引用
黄怡然,张茜,李文迅,董摩扬,李娜,丁婷婷,路问天,严安,郭长青..针刺对骨骼肌急性钝挫伤模型形态学影响的实验观察[J].世界中医药,2014,(4):475-481,7.基金项目
北京中医药大学青年教师自主课题（编号2012-QNJSZX010）；国家级大学生创新创业训练计划项目 （）
