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经皮冠脉介入治疗围手术期心肌损伤影响因素分析

盛建龙 王晓晨 许邦龙 吴继雄 胡章乐

实用医学杂志Issue(5):748-751,4.
实用医学杂志Issue(5):748-751,4.DOI:10.3969/j.issn.1006-5725.2014.05.023

经皮冠脉介入治疗围手术期心肌损伤影响因素分析

Influencing factors of perioperative myocardial injury in patients undergone percutaneous coronary intervention

盛建龙 1王晓晨 1许邦龙 1吴继雄 1胡章乐1

作者信息

  • 1. 230601 合肥市,安徽医科大学第二附属医院心血管内科
  • 折叠

摘要

Abstract

Objective To investigate influencing factors of perioperative myocardial injury in patients undergone percutaneous coronary intervention (PCI). Methods Ninty one patients with coronary heart disease (including stable angina and unstable angina) underwent PCI, the perioperative myocardial injury incidence were observed prospectively by monitoring the preoperative and postoperative high sensitivity troponin protein levels to investigate the influencing factors of perioperative myocardial injury by Logistic regression analysis. Results There were no statistically significance in perioperative myocardial injury incidence (62.5%vs 68.7%, P=0.618) and perioperative myocardial infarction incidence (29.2%vs 20.9%, P=0.411) between stable angina and unstable angina groups . These factors of perioperative myocardial injury in patients undergone PCI by Logistic regression analysis were analysed, and we found that the influencing factors were the application loading dose rosuvastatin before PCI, preoperative statin therapy more than one month, apolipoprotein A levels and total stent length. Conclusion Application loading dose of rosuvastatin before PCI, preoperative statin therapy more than one month, apolipoprotein A levels are related to perioperative myocardial injury reduction, whereas the total length of the stent is associated with an increased occurrence of perioperative myocardial injury.

关键词

血管成形术,经腔,经皮冠状动脉/围手术期心肌损伤/瑞舒伐他汀钙/高敏肌钙蛋白

Key words

Angioplasty, transluminal, percutaneous coronary/Perioperative myocardial injury/Rosuvastatin/High-sensitivity troponin

引用本文复制引用

盛建龙,王晓晨,许邦龙,吴继雄,胡章乐..经皮冠脉介入治疗围手术期心肌损伤影响因素分析[J].实用医学杂志,2014,(5):748-751,4.

基金项目

安徽医科大学校级科研基金资助项目 ()

实用医学杂志

OA北大核心CSTPCD

1006-5725

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