天津科技大学学报Issue(1)：25-29,5.DOI:10.13364/j.issn.1672-6510.2014.01.006
醋酸乌利司他假多晶型分子热分解机理及动力学
Molecular Thermal Decomposition Mechanism and Kinetics of Ulipristal Acetate Pseudo-polymorph
摘要
Abstract
Ulipristal acetate pseudo-polymorph was prepared by cooling crystallization in ethanol.According to TG data,the thermal decomposition of ulipristal acetate pseudo-polymorph included two processes which were desolvation and molecular thermal decomposition as the temperature increased. Non-isothermal thermogravimetry was applied to study the thermal decomposition mechanism and thermal decomposition kinetics of molecular thermal decomposition of ulipristal acetate pseudo-polymorph. Based on different kinetic functions of corresponding molecular thermal decomposition mechanisms and the experimental data of ulipristal acetate pseudo-polymorph,the decomposition mechanism of molecular thermal decompo-sition process was analyzed and estimated,and the corresponding kinetic equation was also obtained.关键词
醋酸乌利司他/假多晶型/非等温热重法/热分解动力学/热分解机理Key words
ulipristal acetate/pseudo-polymorph/non-isothermal thermogravimetry/thermal decomposition kinetics/thermal decomposition mechanism分类
医药卫生引用本文复制引用
雷绒绒,朱亮,沙作良,王彦飞,王海..醋酸乌利司他假多晶型分子热分解机理及动力学[J].天津科技大学学报,2014,(1):25-29,5.基金项目
国家自然科学基金资助项目(21076157)；高等学校博士学科点专项科研基金资助项目(20121208120001) （21076157）
