生态环境学报Issue(1)：122-128,7.
双酚A和壬基酚对河蚬呼吸代谢和抗氧化酶活性的影响
Effects of BPA and NP on respiratory metabolism and antioxidant enzymes in Asian calm
摘要
Abstract
In the present study, the effect of BPA and NP on respiratory metabolism and antioxidant enzymes in Asian clam (Corbicula fluminea) including oxygen consumption rate (OCR), the ammonia excretory rate (AER), and the activity of antioxidant enzymes (superoxide dismutase (SOD) and catalase (CAT)) were studied by semi-static method test.The results showed that: ① the 96 h-LC50 of BPA and NP were 6.34 and 1.09 mg·L-1, respectively, and they were both categorized as high toxic substances; ② BPA and NP had a synergistic effect on chronic and acute toxicity; ③ In the range of the experimental concentrations(BPA:0.63, 0.79 , 1.59, 3.17 mg·L-1;NP:0.109, 0.136, 0.271, 0.542 mg·L-1;BPA+NP:(0.078 2+0.029), (0.097 8+0.036 3), (0.196+0.072 5), (0.391+0.145) mg·L-1), the response of OCR, AER, SOD and CAT to BPA and NP showed a typical pattern. There was only a minor decrease for the OCR, AER, SOD and CAT at low concentrations of BPA, NP and the mixture, and these activities were up-regulated as the concentrations of pollutants were increased, but they were significantly inhibited when the concentration of pollutants were increased up to 1/2 LC50. The present studies indicated that the OCR, AER, SOD and CAT in clams could be considered as an indicator for pEDCs pollution in early stage.关键词
双酚A/壬基酚/河蚬/耗氧率/排氨率/SOD/CATKey words
bisphenol a/nonylphenol/Asian clam (Corbicula fluminea)/oxygen consumption rate (OCR)/ammonia excretory rate (AER)/superoxide dismutase (SOD)/catalase (CAT)分类
资源环境引用本文复制引用
曾丽璇,张悦君,康园,张秋云..双酚A和壬基酚对河蚬呼吸代谢和抗氧化酶活性的影响[J].生态环境学报,2014,(1):122-128,7.基金项目
国家自然科学基金项目(21147003) （21147003）
