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钾扩散耦合引起的心脏中螺旋波的变化

乔成功 王利利 李伟恒 唐国宁

物理学报Issue(19):517-522,6.
物理学报Issue(19):517-522,6.DOI:10.7498/aps.62.198201

钾扩散耦合引起的心脏中螺旋波的变化

Potassium diffusive coupling-induced the variation of spiral wave in cardiac tissues

乔成功 1王利利 1李伟恒 1唐国宁1

作者信息

  • 1. 广西师范大学,物理科学与技术学院,桂林 541004
  • 折叠

摘要

Abstract

In some cases, the extracellular concentration of potassium ions cannot be regarded as being constant. The potassium lateral diffusion leads to extracellular accumulation of potassium ions and the generation of potassium diffusive coupling. The effect of potassium diffusive coupling on spiral wave is investigated by using the Luo-Rudy phase I cardiac model with potassium diffusive coupling. The numerical results show that when the strength of potassium diffusive coupling is relatively strong, the potassium diffusive coupling makes extracellular potassium ion concentration rise first and then regularly oscillate, leading to the irregular meandering of spiral wave. It is observed that the width of spiral arm and the frequency of spiral wave decrease as the strength of potassium diffusive coupling increases. Thus, when the strength of the potassium diffusive coupling is strong enough, the potassium diffusive coupling can eliminate spiral wave and spatiotemporal chaos.

关键词

钾扩散耦合/螺旋波/时空混沌

Key words

potassium diffusive coupling/spiral wave/spatiotemporal chaos

引用本文复制引用

乔成功,王利利,李伟恒,唐国宁..钾扩散耦合引起的心脏中螺旋波的变化[J].物理学报,2013,(19):517-522,6.

基金项目

国家自然科学基金(批准号:11165004)资助的课题 (批准号:11165004)

物理学报

OA北大核心CSCDCSTPCDSCI

1000-3290

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