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胆囊收缩素与神经损伤的修复

陈宣煌 胡荔斌 李荣议 蔡涵华

中国组织工程研究Issue(41):7323-7328,6.
中国组织工程研究Issue(41):7323-7328,6.DOI:10.3969/j.issn.2095-4344.2013.41.021

胆囊收缩素与神经损伤的修复

Cholecystokinin and nerve repair

陈宣煌 1胡荔斌 1李荣议 1蔡涵华1

作者信息

  • 1. 莆田学院附属医院骨科,福建省莆田市 351100
  • 折叠

摘要

Abstract

BACKGROUND:In the past 20 years, cholecystokinin in clinical application and nerve repair has been extensively studied. OBJECTIVE:To explore the role of cholecystokinin in nerve repair and its possible mechanism of action. METHODS:Relevant research results were retrospectively analyzed at the celland organ levels through retrieving recent literatures concerning the biological characteristics of cholecystokinin and its biological role in the nervous system. Then, we summarized the effect of cholecystokinin after nerve injury and its possible RESULTS AND CONCLUSION:Cholecystokinin and its receptors are widely distributed in the body, and under physiological and pathological conditions, their roles were complex and diverse. However, studies addressing the neuroprotective effect of cholecystokinin are not sufficient, most of which are limited to phenomenon observation. Neuroprotective mechanism of cholecystokinin is stil worthy of further studies, which can provide the basis for the clinical application.

关键词

组织构建/组织构建学术探讨/胆囊收缩素/神经损伤/神经系统/神经再生/神经细胞老化/神经元/神经生长因子/神经营养因子/神经递质/保护/修复/省级基金

Key words

cholecystokinin/receptor, cholecystokinin A/receptor, cholecystokinin B/tetragastrin

分类

医药卫生

引用本文复制引用

陈宣煌,胡荔斌,李荣议,蔡涵华..胆囊收缩素与神经损伤的修复[J].中国组织工程研究,2013,(41):7323-7328,6.

基金项目

福建省教育厅A类科技面上项目(JA11212);福建省莆田市医学科技课题计划2012S03(4) (JA11212)

中国组织工程研究

OACSCDCSTPCD

2095-4344

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